9 Compassionate Email Sign-Offs to Replace “Best”

In today’s fast-paced digital world, a simple email sign-off can make or break the tone of your message. Enter compassionate email sign-offs—small but powerful ways to show empathy and build connection in workplace communication. When “Best” feels too cold or generic, these alternatives can soften the edges of professional exchanges. With remote work still shaping how we interact in 2025, closing your emails with warmth matters more than ever. Here are nine thoughtful options to replace the standard farewell, each tailored to add a human touch.

1. Warm Regards

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“Warm Regards” strikes a perfect balance between professional and kind. It conveys genuine care without overstepping boundaries, making it ideal for colleagues or clients you’re on friendly terms with. This sign-off works especially well in follow-up emails or when offering support on a project. It’s a subtle way to show you value the relationship beyond the task at hand.

2. Kindly

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“Kindly” is short, sweet, and to the point. It suggests a gentle tone, often fitting for requests or when you want to soften a directive. Use it when emailing someone you don’t know well or in situations where brevity is key. This sign-off pairs nicely with a quick thank-you to reinforce sincerity.

3. With Appreciation

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“With Appreciation” goes a step further than a standard thank-you. It signals gratitude for the recipient’s time or effort, making it a great choice after collaborative projects or when someone has gone out of their way. This sign-off feels personal yet polished, perfect for managers or mentors.

4. Take Care

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“Take Care” offers a quiet nod to the recipient’s well-being. It’s casual enough for peers but still appropriate in many professional settings, especially during stressful times or when addressing a personal note in a work email. Studies, like those from American Psychological Association, highlight how small gestures of care can reduce workplace stress.

5. Wishing You Well

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“Wishing You Well” carries a heartfelt tone, ideal for closing emails during tough periods or when someone is facing challenges. It’s a compassionate email sign-off that works for both personal and professional contexts, showing you’re thinking of the person beyond the inbox. Use it sparingly to keep its impact strong.

6. Gratefully

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“Gratefully” is a humble and warm way to end a message, especially when you’ve received help or advice. It acknowledges the other person’s contribution directly, fostering a sense of mutual respect. This sign-off suits emails to supervisors or colleagues who’ve supported you on a task.

7. With Kindness

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“With Kindness” is a gentle closer that radiates empathy. It’s a fitting choice for sensitive topics or when you want to ensure your tone isn’t misread as abrupt. This sign-off aligns with findings from Pew Research Center on how digital communication shapes workplace relationships, emphasizing the need for intentional warmth.

8. Cordially

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“Cordially” brings a touch of old-school charm while still feeling friendly. It’s less formal than “Sincerely” but more polished than “Thanks,” making it a versatile option for new contacts or cross-departmental emails. This sign-off quietly nods to respect and goodwill.

9. Stay Well

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“Stay Well” is a modern, caring sign-off that prioritizes the recipient’s health and happiness. It’s especially relevant in 2025, as hybrid work environments continue to blur personal and professional lines. Use this when wrapping up a longer thread or addressing someone you’ve built rapport with over time.